Influenza Vaccines in Maintenance Hemodialysis Patients: Does Seroresponse Vary With Different Vaccine Formulations?

The COVID-19 pandemic has further highlighted the major role of respiratory illnesses as vaccine-preventable sources of morbidity and mortality for patients on dialysis. Influenza-like illnesses contribute to more than 1,000 excess deaths per year among patients with kidney failure, resulting in a seasonal pattern of mortality.1 Influenza can cause viral pneumonia, secondary bacterial pneumonias, and multisystem extrapulmonary complications, including heart failure exacerbation.2 Optimal formulation and timing of influenza vaccinations could decrease the burden of influenza-associated illnesses.