Following aggressive Delta and Omicron waves of COVID, hospitals are grappling with setting vaccine mandates policies to protect patients amidst polarized public opinion. These issues have recently surfaced as many transplant programs remove unvaccinated patients from the waitlist or refuse to list them, making them ineligible for transplant.1,2 We conclude that vaccine mandates are ethical. Yet, concern for possibly increasing health inequities should compel transplant centers to employ techniques such as a patient-centered trauma informed (PCTI) approach when implementing a vaccine requirement.