Estimation of Black-White Disparities in CKD Outcomes: Comparison Using the 2021 Versus the 2009 CKD-EPI Creatinine Equations
Estimated glomerular filtration rate (eGFR) has been commonly used as a measure of kidney function in clinical practice and research. The widely used CKD-EPI creatinine equation uses sex, age, race (Black or non-Black), and serum creatinine level (Scr) to calculate eGFR, assigning a 16% higher eGFR for individuals identified as Black despite the same age, sex, and Scr.1 Because race is a social, nonbiological construct,2,3 to provide a unifying approach for GFR estimation3 a new CKD-EPI creatinine equation that does not use the race variable was recently developed4 and is currently recommended by the National Kidney Foundation and American Society of Nephrology Task Force for US adults.