Kidney Replacement Therapy in the ICU: Less Is More (Death)?

Acute kidney injury (AKI) is a common complication in hospitalized patients that is associated with short- and long-term morbidity and mortality.1 At present, no therapies for AKI exist, apart from supportive care, which may include avoidance of nephrotoxins, volume resuscitation, and blood pressure support, as appropriate.2 When AKI is established or severe, kidney replacement therapy (KRT) may be needed. Peritoneal dialysis is not commonly used in this context; more commonly, intermittent hemodialysis, continuous KRT or a hybrid modality such as prolonged intermittent KRT is used.