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Targeting Endogenous Repair Pathways after AKI

AKI remains a highly prevalent disease associated with...

B7-1 Is Not Induced in Podocytes of Human and Experimental Diabetic Nephropathy

The incidence of progressive kidney disease associated...

Phosphoinositide 3-Kinase-C2{alpha} Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation

Signaling from the primary cilium regulates kidney...

Blocking rpS6 Phosphorylation Exacerbates Tsc1 Deletion-Induced Kidney Growth

The molecular mechanisms underlying renal growth and...

HANAC Syndrome Col4a1 Mutation Causes Neonate Glomerular Hyperpermeability and Adult Glomerulocystic Kidney Disease

Hereditary angiopathy, nephropathy, aneurysms, and...

Essential Role of X-Box Binding Protein-1 during Endoplasmic Reticulum Stress in Podocytes

Podocytes are terminally differentiated epithelial cells...

Loss of Epithelial Membrane Protein 2 Aggravates Podocyte Injury via Upregulation of Caveolin-1

Nephrotic syndrome is a CKD defined by proteinuria with...

Sphingosine 1-Phosphate Receptor 3-Deficient Dendritic Cells Modulate Splenic Responses to Ischemia-Reperfusion Injury

The plasticity of dendritic cells (DCs) permits...

Phosphorylation of Ribosomal Protein S6 Mediates Mammalian Target of Rapamycin Complex 1-Induced Parathyroid Cell Proliferation in Secondary Hyperparathyroidism

Secondary hyperparathyroidism is characterized by...

Serum Indoxyl Sulfate Associates with Postangioplasty Thrombosis of Dialysis Grafts

Hemodialysis vascular accesses are prone to recurrent...

Four-Week Studies of Oral Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor GSK1278863 for Treatment of Anemia

Hypoxia-inducible factor prolyl hydroxylase inhibitors...

Roxadustat (FG-4592): Correction of Anemia in Incident Dialysis Patients

Safety concerns with erythropoietin analogues and...

Spectrum and Prognosis of Noninfectious Renal Mixed Cryoglobulinemic GN

Noninfectious mixed cryoglobulinemic GN (MCGN) has been...

Urinary Sodium and Potassium Excretion and CKD Progression

CKD is a major risk factor for ESRD, cardiovascular...

Predictors of Recurrent AKI

Recurrent AKI is common among patients after...

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