Artículos Científicos en Ingles

Artículos Científicos RSS JASN

Challenges in Rare Variant Association Studies for Complex Kidney Traits: CFHR5 and IgA Nephropathy

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Social Determinants of Racial Disparities in CKD

Significant disparities in CKD rates and outcomes exist...

Role of Receptor Protein Tyrosine Phosphatase {gamma} in Sensing Extracellular CO2 and HCO3-

Regulation of blood pH—critical for virtually every...

TRPC6 G757D Loss-of-Function Mutation Associates with FSGS

FSGS is a CKD with heavy proteinuria that eventually...

Tubular Epithelial NF-{kappa}B Activity Regulates Ischemic AKI

NF-B is a key regulator of innate and adaptive...

Far Upstream Element-Binding Protein 1 Binds the 3' Untranslated Region of PKD2 and Suppresses Its Translation

Autosomal dominant polycystic kidney disease...

Inhibition of EGF Receptor Blocks the Development and Progression of Peritoneal Fibrosis

Inhibitors of EGF receptor (EGFR) have antifibrotic...

Impaired Glucose and Insulin Homeostasis in Moderate-Severe CKD

Kidney disease leads to clinically relevant disturbances...

Distinct Requirements for Vacuolar Protein Sorting 34 Downstream Effector Phosphatidylinositol 3-Phosphate 5-Kinase in Podocytes Versus Proximal Tubular Cells

The mechanisms by which the glomerular filtration...

IgA Structure Variations Associate with Immune Stimulations and IgA Mesangial Deposition

IgA1 mesangial deposition is the hallmark of IgA...

A Novel Extrinsic Pathway for the Unfolded Protein Response in the Kidney

The ribonuclease angiogenin is a component of the...

Renal Handling of Circulating and Renal-Synthesized Hepcidin and Its Protective Effects against Hemoglobin-Mediated Kidney Injury

Urinary hepcidin may have protective effects against AKI...

Candidate Surrogate End Points for ESRD after AKI

AKI, a frequently transient condition, is not accepted...

MicroRNA-489 Induction by Hypoxia-Inducible Factor-1 Protects against Ischemic Kidney Injury

MicroRNAs have been implicated in ischemic AKI. However...

Serum Glucocorticoid-Regulated Kinase 1 Blocks CKD-Induced Muscle Wasting Via Inactivation of FoxO3a and Smad2/3

Muscle proteolysis in CKD is stimulated when the...

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