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Somatic Mutations Modulate Autoantibodies against Galactose-Deficient IgA1 in IgA Nephropathy

Autoantibodies against galactose-deficient IgA1 drive...

Loss of Kynurenine 3-Mono-oxygenase Causes Proteinuria

Changes in metabolite levels of the kynurenine pathway...

2015 Homer W. Smith Award: The Podocyte from Periphery to Center Stage

This overview summarizes selected major developments...

Mendelian Randomization as an Approach to Assess Causality Using Observational Data

Mendelian randomization refers to an analytic approach...

The Current State of Peritoneal Dialysis

Technical innovations in peritoneal dialysis (PD), now...

HEMO Revisited: Why Kt/Vurea Only Tells Part of the Story

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Calcific Uremic Arteriolopathy Revisited

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Bad Memory: CD4 T Cell Presensitization Fosters Antibody-Mediated Kidney Transplant Rejection

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Heme Oxygenase-1 Gene Polymorphisms--Toward Precision Medicine for AKI

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Renal Atp6ap2/(Pro)renin Receptor Is Required for Normal Vacuolar H+-ATPase Function but Not for the Renin-Angiotensin System

ATPase H+-transporting lysosomal accessory...

Dichloroacetate Prevents Cisplatin-Induced Nephrotoxicity without Compromising Cisplatin Anticancer Properties

Cisplatin is an effective anticancer drug; however,...

Vasopressin Regulates Extracellular Vesicle Uptake by Kidney Collecting Duct Cells

Extracellular vesicles (ECVs) facilitate intercellular...

Microbiota-Derived Phenylacetylglutamine Associates with Overall Mortality and Cardiovascular Disease in Patients with CKD

Colonic microbial metabolism substantially contributes...

Kt/Vurea and Nonurea Small Solute Levels in the Hemodialysis Study

The Hemodialysis (HEMO) Study showed that high-dose...

Phosphodiesterase Type 5 Inhibition Reduces Albuminuria in Subjects with Overt Diabetic Nephropathy

Diabetic nephropathy (DN) is the leading cause of ESRD...

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