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Stress Response Gene Nupr1 Alleviates Cyclosporin A Nephrotoxicity In Vivo

Acute tubular damage is a major cause of renal failure,...

A Proposal for a Serology-Based Approach to Membranous Nephropathy

Primary membranous nephropathy (MN) is an autoimmune...

Value of Donor-Specific Anti-HLA Antibody Monitoring and Characterization for Risk Stratification of Kidney Allograft Loss

The diagnosis system for allograft loss lacks accurate...

A Multicenter Study of the Predictive Value of Crescents in IgA Nephropathy

The Oxford Classification of IgA nephropathy does not...

Urinary Angiogenin Reflects the Magnitude of Kidney Injury at the Infrahistologic Level

The ribonuclease angiogenin is a component of the...

BP Control and Long-Term Risk of ESRD and Mortality

We recently showed an association between strict BP...

YKL-40 Associates with Renal Recovery in Deceased Donor Kidney Transplantation

Deceased donor kidneys with AKI are often discarded for...

The Emerging Importance of Non-HLA Autoantibodies in Kidney Transplant Complications

Antibodies that are specific to organ donor HLA have...

Dynamin Autonomously Regulates Podocyte Focal Adhesion Maturation

Rho family GTPases, the prototypical members of which...

Fully Automated Evaluation of Total Glomerular Number and Capillary Tuft Size in Nephritic Kidneys Using Lightsheet Microscopy

The total number of glomeruli is a fundamental parameter...

Toll-Like Receptors 2 and 4 Are Potential Therapeutic Targets in Peritoneal Dialysis-Associated Fibrosis

Peritoneal dialysis (PD) remains limited by dialysis...

MicroRNA-146a in Human and Experimental Ischemic AKI: CXCL8-Dependent Mechanism of Action

AKI leads to tubular injury and interstitial...

An Investigational RNAi Therapeutic Targeting Glycolate Oxidase Reduces Oxalate Production in Models of Primary Hyperoxaluria

Primary hyperoxaluria type 1 (PH1), an inherited rare...

Inhibition of Bromodomain and Extraterminal Domain Family Proteins Ameliorates Experimental Renal Damage

Renal inflammation has a key role in the onset and...

The Genetic Landscape of Renal Complications in Type 1 Diabetes

Diabetes is the leading cause of ESRD. Despite evidence...

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