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Modeling Monogenic Human Nephrotic Syndrome in the Drosophila Garland Cell Nephrocyte

Steroid-resistant nephrotic syndrome is characterized by...

Intercalated Cell Depletion and Vacuolar H+-ATPase Mistargeting in an Ae1 R607H Knockin Model

Distal nephron acid secretion is mediated by highly...

Sildenafil Prevents Podocyte Injury via PPAR-{gamma}-Mediated TRPC6 Inhibition

Transient receptor potential channel C6 (TRPC6) gain-of-...

The Urine Preservative Acetic Acid Degrades Urine Protein: Implications for Urine Biorepositories and the AASK Cohort Study

Patients enrolled in the African American Study of...

Kidney Tubular Ablation of Ocrl/Inpp5b Phenocopies Lowe Syndrome Tubulopathy

Lowe syndrome and Dent disease are two conditions that...

Investigations of Glucocorticoid Action in GN

For several decades, glucocorticoids have been used...

Beneficial Effects of Myo-Inositol Oxygenase Deficiency in Cisplatin-Induced AKI

Overexpression of the proximal tubular enzyme myo...

Mitochondria Protection after Acute Ischemia Prevents Prolonged Upregulation of IL-1{beta} and IL-18 and Arrests CKD

The innate immune system has been implicated in both AKI...

Depletion of Gut Microbiota Protects against Renal Ischemia-Reperfusion Injury

An accumulating body of evidence shows that gut...

Moss-Produced, Glycosylation-Optimized Human Factor H for Therapeutic Application in Complement Disorders

Genetic defects in complement regulatory proteins can...

NF{kappa}B-Induced Periostin Activates Integrin-{beta}3 Signaling to Promote Renal Injury in GN

De novo expression in the kidney of periostin, a...

MHC Class II Risk Alleles and Amino Acid Residues in Idiopathic Membranous Nephropathy

Epitopes of phospholipase A2 receptor (PLA2R), the...

Decoding Acute Myocardial Infarction among Patients on Dialysis

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High-Fat Diet-Induced Lysosomal Dysfunction and Impaired Autophagic Flux Contribute to Lipotoxicity in the Kidney

Excessive fat intake contributes to the progression of...

Lesson Learned in Mortality and Kidney Transplant Outcomes among Pediatric Dialysis Patients

Este artículo no posee resumen

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