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Precision Transplant Medicine: Biomarkers to the Rescue

The concept that individuals with the same disease and a...

Factor H Competitor Generated by Gene Conversion Events Associates with Atypical Hemolytic Uremic Syndrome

Atypical hemolytic uremic syndrome (aHUS), a rare form...

Novel Insights into the Pathogenesis of Monogenic Congenital Anomalies of the Kidney and Urinary Tract

Congenital anomalies of the kidneys and urinary tract (...

Opposing Roles of Dendritic Cell Subsets in Experimental GN

Dendritic cells (DCs) are thought to form a dendritic...

DnaJ Heat Shock Protein Family B Member 9 Is a Novel Biomarker for Fibrillary GN

Fibrillary GN (FGN) is a rare primary glomerular disease...

Aldosterone Is Essential for Angiotensin II-Induced Upregulation of Pendrin

The renin-angiotensin-aldosterone system has an...

MYH9 E1841K Mutation Augments Proteinuria and Podocyte Injury and Migration

Intronic variants of the MYH9 gene that encodes...

Cardiovascular Effects of Renal Distal Tubule Deletion of the FGF Receptor 1 Gene

The bone-derived hormone fibroblast growth factor–23 (...

Kidney Proximal Tubule Lipoapoptosis Is Regulated by Fatty Acid Transporter-2 (FATP2)

Albuminuria and tubular atrophy are among the highest...

ShcA Adaptor Protein Promotes Nephrin Endocytosis and Is Upregulated in Proteinuric Nephropathies

Nephrin is a key structural component of the podocyte...

Endotoxin Preconditioning Reprograms S1 Tubules and Macrophages to Protect the Kidney

Preconditioning with a low dose of endotoxin confers...

Collectin-11 Promotes the Development of Renal Tubulointerstitial Fibrosis

Collectin-11 is a recently described soluble C-type...

Genetic Complexity of Autosomal Dominant Polycystic Kidney and Liver Diseases

Data indicate significant phenotypic and genotypic...

Neutralizing Antibody-Mediated Response and Risk of BK Virus-Associated Nephropathy

BK virus–associated nephropathy (BKVAN) causes renal...

Particulate Matter Air Pollution and the Risk of Incident CKD and Progression to ESRD

Elevated levels of fine particulate matter <2.5 µ...

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