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Breast Regression Protein-39/Chitinase 3-Like 1 Promotes Renal Fibrosis after Kidney Injury via Activation of Myofibroblasts

The normal response to kidney injury includes a robust...

Hepatocyte Nuclear Factor-1{beta} Controls Mitochondrial Respiration in Renal Tubular Cells

AKI is a frequent condition that involves renal...

Endothelial NF-{kappa}B Blockade Abrogates ANCA-Induced GN

ANCA-associated vasculitis (AAV) is a highly...

A Missense Mutation in the Extracellular Domain of {alpha}ENaC Causes Liddle Syndrome

Liddle syndrome is an autosomal dominant form of...

Lysophosphatidic Acid Receptor Antagonism Protects against Diabetic Nephropathy in a Type 2 Diabetic Model

Lysophosphatidic acid (LPA) functions through activation...

PGC-1{alpha} Protects from Notch-Induced Kidney Fibrosis Development

Kidney fibrosis is the histologic manifestation of CKD....

Characterization and Correction of Olfactory Deficits in Kidney Disease

Patients with CKD suffer from food aversion, anorexia,...

Association Analysis of the MHC in Lupus Nephritis

Lupus nephritis (LN) is one of the most prevalent and...

Urinary Matrix Metalloproteinase-7 Predicts Severe AKI and Poor Outcomes after Cardiac Surgery

Urinary matrix metalloproteinase-7 (uMMP-7) levels...

Urinary Extracellular Vesicles of Podocyte Origin and Renal Injury in Preeclampsia

Renal histologic expression of the podocyte-specific...

Class II Eplet Mismatch Modulates Tacrolimus Trough Levels Required to Prevent Donor-Specific Antibody Development

Despite more than two decades of use, the optimal...

The Loss of GSTM1 Associates with Kidney Failure and Heart Failure

Glutathione S-transferase mu 1 (GSTM1) encodes an...

Association between Endothelin-1 Levels and Kidney Disease among Blacks

Endothelin-1, a marker of endothelial dysfunction, is a...

Regulation of Nephron Progenitor Cell Self-Renewal by Intermediary Metabolism

Nephron progenitor cells (NPCs) show an age-dependent...

Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy

Established therapies for diabetic nephropathy (dNP)...

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