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The NLRP3 Inflammasome Has a Critical Role in Peritoneal Dialysis-Related Peritonitis

Bacterial peritonitis remains the main cause of...

Macrophage-to-Myofibroblast Transition Contributes to Interstitial Fibrosis in Chronic Renal Allograft Injury

Interstitial fibrosis is an important contributor to...

Comparing Outcomes between Antibody Induction Therapies in Kidney Transplantation

Kidney transplant recipients often receive antibody...

Sickle Cell Trait and the Risk of ESRD in Blacks

Blacks, compared with whites, have an increased risk of...

Global Cardiovascular and Renal Outcomes of Reduced GFR

The burden of premature death and health loss from ESRD...

Hydrodynamic Isotonic Fluid Delivery Ameliorates Moderate-to-Severe Ischemia-Reperfusion Injury in Rat Kidneys

Highly aerobic organs like the kidney are innately...

Galactosylation of IgA1 Is Associated with Common Variation in C1GALT1

IgA nephropathy (IgAN), an important cause of kidney...

Targeting mTOR Signaling Can Prevent the Progression of FSGS

Mammalian target of rapamycin (mTOR) signaling is...

A Novel Inhibitor of Homeodomain Interacting Protein Kinase 2 Mitigates Kidney Fibrosis through Inhibition of the TGF-{beta}1/Smad3 Pathway

Homeodomain interacting protein kinase 2 (HIPK2) is a...

Deficiency of the Angiotensinase Aminopeptidase A Increases Susceptibility to Glomerular Injury

Aminopeptidase A (APA) is expressed in glomerular...

Quantitative Three-Dimensional Tissue Cytometry to Study Kidney Tissue and Resident Immune Cells

Analysis of the immune system in the kidney relies...

IL-33-Mediated Expansion of Type 2 Innate Lymphoid Cells Protects from Progressive Glomerulosclerosis

Innate lymphoid cells (ILCs) have an important role in...

Education in Nephrology Fellowship: A Survey-Based Needs Assessment

Educational needs assessments for nephrology fellowship...

IL-36 Signaling Facilitates Activation of the NLRP3 Inflammasome and IL-23/IL-17 Axis in Renal Inflammation and Fibrosis

IL-36 cytokines are proinflammatory and have an...

Uromodulin in the Bloodstream: Old Wine in a New Wineskin

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